Activation of NPY2R-expressing amygdala neurons inhibits itch behavior in mice without lateralization

CEA (Central amygdalar nucleus) MBA:536 projects to PB (Parabrachial nucleus) MBA:867 · Mouse

Labelled axons from NPY2R-positive CeA neurons expressing ChrimsonR-tdTomato were detected in the parabrachial nucleus.

Fig. 6D; Results, projection tracing section

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

CEA (Central amygdalar nucleus) MBA:536 projects to PAG (Periaqueductal gray) MBA:795 · Mouse

Anterograde labelling from Cre-dependent tdTomato-tagged opsin expression in NPY2R-positive CeA neurons revealed labelled axons in the ventrolateral periaqueductal gray.

Fig. 6B; Results, projection tracing section

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

CEA (Central amygdalar nucleus) MBA:536 projects to MB (Midbrain) MBA:313 · Mouse

tdTomato-labelled fibers arising from virally transduced NPY2R-positive CeA neurons were found in the substantia nigra.

Fig. 6C; Results, projection tracing section

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

CEA (Central amygdalar nucleus) MBA:536 projects to BST (Bed nuclei of the stria terminalis) MBA:351 · Mouse

Cre-dependent ChrimsonR-tdTomato expressed in NPY2R-positive CeA neurons of Npy2r-cre mice produced clear tdTomato-labelled fibers in the bed nucleus of the stria terminalis.

Fig. 6A; Results, projection tracing section

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

CEA (Central amygdalar nucleus) MBA:536 projects to LHA (Lateral hypothalamic area) MBA:194 · Mouse

Although the lateral hypothalamus was examined as a candidate target, no tdTomato-labelled projections from NPY2R-positive CeA neurons were seen there.

Results, projection tracing section (Fig. 6)

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.