clm-kcv2rvdjgw

ACA (Anterior cingulate area) functionally connects to BLA glutamatergic principal neurons

Species: Mouse
Result: present
Method: optogenetic circuit mapping
Sign: excitatory
Evidence: Light stimulation of ChR2-expressing anterior cingulate axons in slices produced AMPAR- and NMDAR-mediated excitatory postsynaptic currents in BLA pyramidal neurons, establishing a functional ACC-to-BLA excitatory synapse.
Source: Stress induces insertion of calcium-permeable AMPA receptors in the OFC–BLA synapse and modulates emotional behaviours in mice
Translational Psychiatry, 2020
DOI 10.1038/s41398-020-0837-3 · PubMed 32424318 · PMC7235080, Fig. 2l,m
Licence: CC-BY-4.0
Named in the paper: “ACC” and “BLA pyramidal neurons”
Made by: an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5-5) agrees, 2026-10-09
“Light-evoked EPSCs with AMPAR and NMDAR components were recorded in BLA pyramidal neurons from ChR2-expressing ACC axons, shown in Fig. 2l,m.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.