clm-ksxnnc3av4

PVT (Paraventricular nucleus of the thalamus) projects to CEA (Central amygdalar nucleus)

Species: Mouse
Result: present
Method: anterograde tracer
Sign: unknown
Evidence: Cre-dependent anterograde tracing in Vglut2-Cre mice showed mRuby-labelled terminals from pPVT glutamatergic neurons in the central amygdala.
Source: The pPVTglu- CeAGABA circuit is involved in regulating hyperalgesia in the chronic NTG mouse model in males
The Journal of Headache and Pain, 2026
DOI 10.1186/s10194-026-02285-3 · PubMed 41652327 · PMC12977853, Fig. 3A-B
Licence: CC-BY-NC-ND-4.0
Named in the paper: “pPVT” and “CeA”
Made by: an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5) agrees, 2026-10-09
“mRuby terminals in CeA reported from pPVT Vglut2+ neurons.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.