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PL (Prelimbic area) synapses onto PVH (Paraventricular hypothalamic nucleus)

All claims for this connection
Species
Mouse
Result
absent
Method
transsynaptic tracer
Sign
unknown
Evidence
In the same anterograde transsynaptic labelling experiment, the transsynaptically labelled PVN neurons were not immunoreactive for oxytocin, so no direct prelimbic input onto PVN oxytocin neurons was detected.
Source

Conditional deletion of Cc2d1a increases irritability-like behavior by decreasing oxytocin expression via the prelimbic-hypothalamic pathway

Journal of Biomedical Science, 2026

DOI 10.1186/s12929-026-01263-w · PubMed 42231358 · PMC13227712, Fig. 6D, F

Licence: CC-BY-4.0

Named in the paper
“PrL” and “PVN OXT-expressing neurons”
Made by
an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by

a second AI model (claude-opus-5) agrees, 2026-10-09

“Anterograde transsynaptic labeling showed PVN labeled cells were not OXT-immunoreactive, supporting absence of direct input.”

Status

proposed

Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.