clm-mkk6dm59w1

BLA (Basolateral amygdalar nucleus) functionally connects to ACA (Anterior cingulate area)

Species: Mouse
Result: present
Method: optogenetic circuit mapping
Sign: unknown
Evidence: In mice expressing ChR2 in the BLA, 20 Hz blue light delivered to BLA terminals in the ACC raised c-Fos expression in the ACC relative to mCherry controls. Yellow-light NpHR inhibition tended to have the opposite effect.
Source: Activation of basolateral amygdala to anterior cingulate cortex circuit alleviates MK-801 induced social and cognitive deficits of schizophrenia
Frontiers in Cellular Neuroscience, 2022
DOI 10.3389/fncel.2022.1070015 · PubMed 36619672 · PMC9813383, Fig. 5A-C
Licence: CC-BY-4.0
Named in the paper: “BLA” and “ACC”
Made by: an AI model reading the paper (claude-opus-5-5, extract@0.3.0), 2026-10-10
Checked by: a second AI model (claude-opus-5-5) agrees, 2026-10-10
“Blue-light stimulation of BLA ChR2 terminals in the ACC raised ACC c-Fos over mCherry controls (p=0.047), and the paper calls the NpHR effect roughly opposite; sign stays unknown.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.