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PL (Prelimbic area) projects to PAG (Periaqueductal gray)

Species: Mouse
Result: present
Method: retrograde tracer
Sign: unknown
Evidence: Retrograde cholera toxin B injected into the periaqueductal gray labelled pyramidal tract neurons in layer 5 of PL, which were then targeted for recording.
Source: Rostral and caudal basolateral amygdala engage distinct circuits in the prelimbic and infralimbic prefrontal cortex
eLife, 2022
DOI 10.7554/elife.82688 · PubMed 36476757 · PMC9803354, Fig. 2A; Fig. 2—figure supplement 1J
Licence: CC-BY-4.0
Named in the paper: “PL” and “periaqueductal gray (PAG)”
Made by: an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-10
Checked by: a second AI model (claude-opus-5) agrees, 2026-10-10
“PAG retrograde labelling identified PL L5 PT neurons used for recordings.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.