Mouse

PL (Prelimbic area) projects to PAG (Periaqueductal gray)

2 claims from 1 source: 2 found, 0 tested and absent, 0 ambiguous. Evidence: anterograde tracer, retrograde tracer. Strongest reported: strong.

The claims behind it

clm-anwwa3jt6wpresentretrograde tracerproposed

Retrograde AAV2/R carrying mCherry injected into the lateral/ventrolateral PAG labelled CaMKIIα-positive PrL neurons, almost all of them in layer 5 and distinct from the BLA-projecting population.

DOI 10.1172/jci166356 · PubMed 36917193 · PMC10145931, Fig. 1A–C; Supplemental Fig. 1A–G

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); not checked yet.

clm-x33vxwa888presentanterograde tracerstrength: strongproposed

After injecting an AAV expressing mCherry into the PrL, the authors saw extensive labelled axonal fibers in the lateral/ventrolateral PAG.

DOI 10.1172/jci166356 · PubMed 36917193 · PMC10145931, Supplemental Fig. 6A

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); not checked yet.