clm-nh9d6xf145
BLA (Basolateral amygdalar nucleus) functionally connects to BLA glutamatergic principal neurons
All claims for this connection- Species
- Mouse
- Result
- present
- Method
- optogenetic circuit mapping
- Sign
- inhibitory
- Evidence
- Optical activation of raphe axons at 20 Hz raised the frequency of spontaneous IPSCs in basal amygdala principal neurons; these events were abolished by GABA-A and GABA-B antagonists but not by a 5-HT1A antagonist, indicating a disynaptic GABAergic input from locally excited interneurons onto principal neurons.
- Source
Control of Amygdala Circuits by 5-HT Neurons via 5-HT and Glutamate Cotransmission
The Journal of Neuroscience, 2017
DOI 10.1523/jneurosci.2238-16.2016 · PubMed 28087766 · PMC5320609, Fig. 5E,FLicence: CC-BY-NC-SA-4.0
- Named in the paper
- “BA interneurons (INs)” and “BA principal neurons (PNs)”
- Made by
- an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-10
- Checked by
a second AI model (claude-opus-5) agrees, 2026-10-10
“Light-evoked sIPSC increase in PNs blocked by GABA antagonists but not WAY, indicating disynaptic IN→PN inhibition.”
- Status
proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.