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Isocortex functionally connects to BLA (basal amygdaloid nucleus)
All claims for this connection- Species
- Rat
- Result
- present
- Method
- optogenetic circuit mapping
- Sign
- excitatory
- Evidence
- In slices, green-light silencing of ArchT-expressing lOFC axons and terminals in the BLA lowered the frequency of spontaneous EPSCs (recorded under GABAA blockade) in most recorded BLA neurons, indicating excitatory lOFC drive onto BLA cells.
- Measurements
- connection probability: 0.667, n = 12
- Source
A bidirectional corticoamygdala circuit for the encoding and retrieval of detailed reward memories
eLife, 2021
DOI 10.7554/elife.68617 · PubMed 34142660 · PMC8266390, Fig. 4—figure supplement 1Licence: CC-BY-4.0
- Named in the paper
- “lateral orbitofrontal cortex (lOFC)” and “basolateral amygdala (BLA)”
- Made by
- an AI model reading the paper (claude-opus-5-5, extract@0.3.0), 2026-10-10
- Checked by
a second AI model (claude-opus-5) agrees, 2026-10-10
“Ex vivo optical silencing of ArchT-expressing lOFC terminals reduced BLA sEPSC frequency in 8 of 12 cells, supporting an excitatory functional input and the 8/12 figure.”
- Status
proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.