clm-p761xzm84t
P (Pons) projects to MY (Medulla)
All claims for this connection- Species
- Rat
- Result
- present
- Method
- retrograde tracer
- Sign
- unknown
- Evidence
- After AAV-driven overexpression of human alpha-synuclein restricted to medullary neurons (vagus nerve injection), immunoreactive axons appeared in the pons by 8 weeks and increased markedly by 18 weeks, both ipsilateral and, at roughly a third of the ipsilateral count, contralateral to the injection; the authors attribute this to transfer of the protein into fibres of pontine neurons that innervate the medulla.
- Source
Caudo‐rostral brain spreading of α‐synuclein through vagal connections
EMBO Molecular Medicine, 2013
DOI 10.1002/emmm.201302475 · PubMed 23703938 · PMC3721477, Fig 2A–D, Results (spreading section)Licence: CC-BY-3.0
- Named in the paper
- “pons” and “medulla oblongata (MO)”
- Made by
- an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
- Checked by
a second AI model (claude-opus-5) agrees, 2026-10-09
“Pontine hα-syn axons at 8 and 18 weeks with ~35% contralateral/ipsilateral ratio match the reported counts.”
- Status
proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.