clm-pabsmpmc90

AI (Agranular insular area) functionally connects to CEA (Central amygdalar nucleus)

Species: Mouse
Result: absent
Method: optogenetic circuit mapping
Sign: unknown
Evidence: Photostimulating the terminals of the same intersectionally labelled insular neurons failed to evoke excitatory currents in central amygdala neurons, confirming the pathway's selectivity for the accumbens.
Source: Insular cortical circuits as an executive gateway to decipher threat or extinction memory via distinct subcortical pathways
Nature Communications, 2022
DOI 10.1038/s41467-022-33241-9 · PubMed 36130959 · PMC9492683, Supplementary Fig. 25
Licence: CC-BY-4.0
Named in the paper: “IC neurons in the OFC → IC → NAc pathway” and “CeA”
Made by: an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5) agrees, 2026-10-09
“Terminals of intersectionally labeled OFC→IC→NAc neurons evoked no currents in CeA.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.