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PB (Parabrachial nucleus) projects to CEA (central amygdaloid nucleus)

Species: Rat
Result: present
Method: single neuron reconstruction
Sign: unknown
Evidence: A single KF neuron filled with neurobiotin in vivo had an axon that entered the superior cerebellar peduncle and gave rise to labelled terminals in the capsular central amygdala; the labelled terminals in CeC were apposed to PACAP-immunoreactive perisomatic profiles. Only one of 14 attempted recordings yielded a fully labelled KF neuron.
Source: Kölliker–Fuse/Parabrachial Complex PACAP—Glutamate Pathway to the Extended Amygdala Couples Rapid Autonomic and Delayed Endocrine Responses to Acute Hypotension
International Journal of Molecular Sciences, 2025
DOI 10.3390/ijms262311405 · PubMed 41373566 · PMC12692419, Results (juxtacellular labeling section); Fig. 5A,C,E,F
Licence: CC-BY-4.0
Named in the paper: “Kölliker–Fuse nucleus (KF), ventrolateral parabrachial complex” and “capsular central amygdala (CeC)”
Made by: an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-10
Checked by: a second AI model (claude-opus-5) agrees, 2026-10-10
“Results and Fig. 5C,E support the single labeled KF neuron's axon in SCP and PACAP-apposed terminals in CeC, with one fully labeled cell of 14 attempts.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.