clm-qdhn38d1cw

ARH (Arcuate hypothalamic nucleus) projects to VTA (Ventral tegmental area)

Species: Mouse
Result: present
Method: retrograde tracer
Sign: unknown
Strength: strong
Evidence: Both CTB and fluorescent microspheres injected into the VTA retrogradely labeled arcuate POMC neurons, about 5-6% of them. Contralateral labeling was significantly lower than ipsilateral, and labeled cells were distributed evenly along the arcuate.
Source: Relative Number and Distribution of Murine Hypothalamic Proopiomelanocortin Neurons Innervating Distinct Target Sites
PLoS ONE, 2011
DOI 10.1371/journal.pone.0025864 · PubMed 21991375 · PMC3186811, Fig. 1A-B, Fig. 3, Fig. 4C, Fig. 5B, Fig. 6B
Licence: CC-BY-4.0
Named in the paper: “arcuate nucleus (POMC neurons)” and “ventral tegmental area”
Made by: an AI model reading the paper (claude-opus-5-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5-5) disagrees, 2026-10-09
“The significantly lower contralateral VTA labeling applies to total CTB cells; the percent of POMC cells labeled did not differ between sides.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.