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CP (Caudoputamen) projects to MOs (Secondary motor area)

Species: Mouse
Result: present
Method: anterograde tracer
Sign: unknown
Evidence: AAV-hSyn-mCherry injected into the dorsal striatum labelled fibres/cells in the secondary motor cortex in wild-type and control mice; the mCherry signal there was markedly weaker (about 34% of wild-type intensity) after CDK5 knockdown in the dorsal striatum.
Source: Downregulation of CDK5 signaling in the dorsal striatum alters striatal microcircuits implicating the association of pathologies with circadian behavior in mice
Molecular Brain, 2022
DOI 10.1186/s13041-022-00939-2 · PubMed 35701839 · PMC9195255, Fig. 7A–D
Licence: CC-BY-4.0
Named in the paper: “dorsal striatum (DS)” and “secondary motor cortex (M2)”
Made by: an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5) agrees, 2026-10-09
“Anterograde tracing shows DS labeling in M2, reduced to ~34% of WT in KD mice.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.