clm-r2mtgz318w

Rat central amygdala corticotropin-releasing hormone-expressing neurons projects to CP (Caudoputamen)

Species: Rat
Result: present
Method: retrograde tracer
Sign: unknown
Evidence: After infusing a retrograde Cre-dependent AAV expressing GFP into the dorsal striatum of CRF-Cre;tdTomato rats, GFP-labelled cells overlapping with tdTomato (CRF+) were found in the central amygdala, showing that CeA CRF neurons send axons to the dorsal striatum; the proportion and density of such projecting CRF neurons was lower in CeA than in BNST (9 sections from 5 rats).
Source: Alcohol attenuates CRF-induced excitatory effects from the extended amygdala to dorsostriatal cholinergic interneurons
eLife, 2026
DOI 10.7554/elife.107145 · PubMed 41870239 · PMC13008356, Fig. 3A, 3C–3F
Licence: CC-BY-4.0
Named in the paper: “CeA CRF+ (tdTomato+) neurons” and “dorsal striatum”
Made by: an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-10
Checked by: a second AI model (claude-opus-5) agrees, 2026-10-10
“Retrograde Cre-dependent GFP revealed CeA CRF+ neurons projecting to rat dorsal striatum, fewer than BNST.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.