clm-rfz07mpn5b
PL (Prelimbic area) functionally connects to ACB (Nucleus accumbens)
All claims for this connection- Species
- Mouse
- Result
- absent
- Method
- optogenetic circuit mapping
- Sign
- unknown
- Evidence
- Despite dense prefrontal D1 axon labelling there, 20 Hz photostimulation of prefrontal D1 neurons produced no detectable change in Fos immunoreactivity in the nucleus accumbens.
- Source
Medial prefrontal D1 dopamine neurons control food intake
Nature Neuroscience, 2014
DOI 10.1038/nn.3625 · PubMed 24441680 · PMC3968853, Supplemental Fig. 7d,e; Results, 'Downstream targets of mPFC stimulation'- Named in the paper
- “medial prefrontal cortex (mPFC)” and “nucleus accumbens”
- Made by
- an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
- Checked by
a second AI model (claude-opus-5) agrees, 2026-10-09
“Paper explicitly found no Fos difference in nucleus accumbens despite dense axons.”
- Status
proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.