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PL (Prelimbic area) projects to BLA (Basolateral amygdalar nucleus)

All claims for this connection
Species
Mouse
Result
present
Method
anterograde tracer
Sign
unknown
Strength
strong
Evidence
Cre-dependent ChR2-eYFP expressed in D1-receptor neurons of the medial prefrontal cortex (prelimbic and infralimbic) of Drd1a-cre mice labelled axons that were prominent in the caudomedial basolateral amygdala. A Cre-dependent synaptobrevin-eGFP virus injected in the same prefrontal site produced punctate presynaptic labelling in the same amygdala territory, with puncta lying within 5 microns of CaMKII-positive cell bodies.
Source

Medial prefrontal D1 dopamine neurons control food intake

Nature Neuroscience, 2014

DOI 10.1038/nn.3625 · PubMed 24441680 · PMC3968853, Fig. 5a,g,h; Results, 'Downstream targets of mPFC stimulation'
Named in the paper
“medial prefrontal cortex (mPFC)” and “caudal-medial, basolateral nucleus of the amygdala (mBLA)”
Made by
an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by

a second AI model (claude-opus-5) agrees, 2026-10-09

“ChR2-eYFP and synaptobrevin-eGFP anterograde labeling show prominent prefrontal D1 terminals apposed to CaMKII cells in mBLA.”

Status

proposed

Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.