clm-s782sbzj71

CTX (Cerebral cortex) synapses onto CP (Caudoputamen)

Species: Mouse
Result: present
Method: transsynaptic tracer
Sign: unknown
Evidence: Rabies tracing from pDMS D2-MSNs labeled many cortical neurons. The cortex was the largest input source, though proportionally smaller than for D1-MSNs.
Source: Whole-Brain Mapping of Direct Inputs to Dopamine D1 and D2 Receptor-Expressing Medium Spiny Neurons in the Posterior Dorsomedial Striatum
eneuro, 2020
DOI 10.1523/eneuro.0348-20.2020 · PubMed 33380525 · PMC7877463, Fig. 1D, 1F
Named in the paper: “cortex” and “D2-MSNs in the posterior dorsomedial striatum (pDMS)”
Made by: an AI model reading the paper (claude-opus-5-5, extract@0.3.0), 2026-10-10
Checked by: a second AI model (claude-opus-5-5) agrees, 2026-10-10
“The cortex is the main input source to both MSN types but favors D1-MSNs (p<0.01).”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.