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AUD (Auditory areas) functionally connects to LA glutamatergic principal neurons

Species: Mouse
Result: present
Method: optogenetic circuit mapping
Sign: excitatory
Evidence: Blue-light activation of ChR2-expressing auditory cortex terminals in slices evoked EPSCs in lateral amygdala pyramidal neurons. These currents were abolished by TTX and restored by 4-AP, consistent with direct terminal activation, and were blocked by CNQX, showing they were glutamatergic.
Source: Modulation of Long-Term Potentiation of Cortico-Amygdala Synaptic Responses and Auditory Fear Memory by Dietary Polyunsaturated Fatty Acid
Frontiers in Behavioral Neuroscience, 2016
DOI 10.3389/fnbeh.2016.00164 · PubMed 27601985 · PMC4993868, Fig. 2C-D; Results, Optogenetic Isolation of Synaptic Responses
Named in the paper: “auditory cortex (ACx)” and “pyramidal neurons in the LA”
Made by: an AI model reading the paper (claude-opus-5-5, extract@0.3.0), 2026-10-10
Checked by: a second AI model (claude-opus-5-5) agrees, 2026-10-10
“Fig. 2C-D and the Results show light-evoked EPSCs in mouse LA pyramidal neurons that are TTX-sensitive, 4-AP-rescued and CNQX-blocked, so a monosynaptic glutamatergic excitatory input is supported.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.