Modulation of Long-Term Potentiation of Cortico-Amygdala Synaptic Responses and Auditory Fear Memory by Dietary Polyunsaturated Fatty Acid

AUD (Auditory areas) MBA:247 projects to LA (Lateral amygdalar nucleus) MBA:131 · Mouse

AAV2-CaMKIIa-ChR2-EYFP was injected into the auditory cortex. Four to five weeks later, EYFP-labelled fibres and presynaptic puncta were seen in the lateral amygdala.

Fig. 2A-B

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AUD (Auditory areas) MBA:247 functionally connects to LA glutamatergic principal neurons nt-659aayyts5 · Mouse

Blue-light activation of ChR2-expressing auditory cortex terminals in slices evoked EPSCs in lateral amygdala pyramidal neurons. These currents were abolished by TTX and restored by 4-AP, consistent with direct terminal activation, and were blocked by CNQX, showing they were glutamatergic.

Fig. 2C-D; Results, Optogenetic Isolation of Synaptic Responses

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.