clm-v5n5c299vj

PB (Parabrachial nucleus) projects to CEA (Central amygdalar nucleus)

Species: Mouse
Result: present
Method: anterograde tracer
Sign: unknown
Strength: strong
Evidence: Cre-dependent ChR2-mCherry injected into the PBN of CaMKII-Cre mice labelled cell bodies in the PBN and produced abundant mCherry-positive axonal fibers in the CeA.
Source: Switching of delta opioid receptor subtypes in central amygdala microcircuits is associated with anxiety states in pain
Journal of Biological Chemistry, 2021
DOI 10.1016/j.jbc.2021.100277 · PubMed 33428940 · PMC7948800, Fig. 4, A and B
Licence: CC-BY-4.0
Named in the paper: “PBN” and “CeA”
Made by: an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5-5) agrees, 2026-10-09
“Fig. 4B shows PBN expression and robust mCherry-positive fibers in the CeA, which supports a strong anterograde projection.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.