clm-wpe899nw18

BLA (Basolateral amygdalar nucleus) functionally connects to ILA (Infralimbic area)

Species: Mouse
Result: present
Method: optogenetic circuit mapping
Sign: excitatory
Evidence: Light activation of ChR2+ BLA axons in slices evoked EPSCs in IL neurons that mostly persisted in TTX/4-AP, indicating monosynaptic excitation. IPSCs were abolished by the blockers, so the inhibition was polysynaptic. Monosynaptic input was larger in L5 cortico-PAG neurons than in L3/5 corticoamygdalar neurons, and larger in L3/5 than in L2 corticoamygdalar neurons.
Source: Specific Targeting of the Basolateral Amygdala to Projectionally Defined Pyramidal Neurons in Prelimbic and Infralimbic Cortex
eneuro, 2016
DOI 10.1523/eneuro.0002-16.2016 · PubMed 27022632 · PMC4804386, Fig. 2D-G; Fig. 3B-D, J-L; Fig. 4D-I
Licence: CC-BY-NC-SA-4.0
Named in the paper: “basolateral amygdala (BLA)” and “IL cortex (L5 IL-CP neurons, L2 and L3/5 IL-CA neurons)”
Made by: an AI model reading the paper (claude-opus-5-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5-5) agrees, 2026-10-09
“IL EPSCs largely survived the blockers and IPSCs were abolished, and the paired comparisons favour L5 CP over L3/5 CA and L3/5 CA over L2 CA.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.