clm-wym81hpweq

PL (Prelimbic area) projects to CNU (Cerebral nuclei)

Species: Mouse
Result: present
Method: retrograde tracer
Sign: unknown
Evidence: After retrograde Cre-dependent AAV injection into the IPAC of D1-cre mice, EYFP-labelled D1-expressing deep-layer pyramidal neurons were found in PL, though with somewhat lower signal intensity than in IL.
Source: Social defeat stress-specific increase in c-Fos expression in the extended amygdala in mice: Involvement of dopamine D1 receptor in the medial prefrontal cortex
Scientific Reports, 2019
DOI 10.1038/s41598-019-52997-7 · PubMed 31723165 · PMC6854085, Fig. 4c,d; Results, 'D1-expressing mPFC pyramidal neurons send direct projections to the IPAC'
Licence: CC-BY-4.0
Named in the paper: “prelimbic cortex (PL)” and “interstitial nucleus of the posterior limb of the anterior commissure (IPAC)”
Made by: an AI model reading the paper (claude-opus-5-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5) agrees, 2026-10-09
“PL also contained EYFP-labelled neurons, quantified in Fig. 4d with a nonsignificant trend lower than IL.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.