clm-xk8tc6218g

CTX (Cerebral cortex) functionally connects to LA glutamatergic principal neurons

Species: Mouse
Result: present
Method: electrical stimulation
Sign: excitatory
Evidence: In acute coronal slices, stimulating cortical afferents in the external capsule evoked monosynaptic EPSCs with AMPA and NMDA components in patched LA principal neurons, in both juvenile and adult mice. The same stimulation also produced picrotoxin-sensitive feed-forward IPSCs. The paper tracked how paired-pulse ratio, refilling rate and maximal EPSC changed with age, and tested associative LTP at these synapses.
Source: Synaptic Maturation at Cortical Projections to the Lateral Amygdala in a Mouse Model of Rett Syndrome
PLoS ONE, 2010
DOI 10.1371/journal.pone.0011399 · PubMed 20625482 · PMC2896423, Fig. 1A, Fig. 2, Fig. 3, Fig. 4; Results
Licence: CC-BY-4.0
Named in the paper: “cortical axons in the external capsule (Cortico-LA projections)” and “LA principal neurons”
Made by: an AI model reading the paper (claude-opus-5-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5-5) agrees, 2026-10-09
“External-capsule stimulation evoked monosynaptic EPSCs in mouse LA principal cells, and the paper reports age-dependent PPR, refilling and EPSCmax changes, NMDA/AMPA ratios, LTP and feed-forward IPSCs.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.