clm-xx9gzf97ka

PL (Prelimbic area) functionally connects to BLA (Basolateral amygdalar nucleus)

Species: Mouse
Result: present
Method: optogenetic circuit mapping
Sign: unknown
Evidence: Optogenetic activation of PL ChCs produced a positive-going evoked potential in the ipsilateral BLA LFP 5-10 ms after light onset, interpreted as reduced PL-to-BLA drive.
Source: Selective inhibitory control of pyramidal neuron ensembles and cortical subnetworks by chandelier cells
Nature Neuroscience, 2017
DOI 10.1038/nn.4624 · PubMed 28825718 · PMC5614838, Fig. 5h
Named in the paper: “PL L2 chandelier cells (ChCs)” and “BLA”
Made by: an AI model reading the paper (claude-opus-5-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5-5) agrees, 2026-10-09
“ChC photoactivation produced a positive-going BLA evoked potential at 5-10 ms that differed from eYFP controls; the effect is indirect, via PL pyramidal cells.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.