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BLA (basal amygdaloid nucleus) functionally connects to Isocortex
All claims for this connection- Species
- Rat
- Result
- present
- Method
- electrical stimulation
- Sign
- unknown
- Evidence
- In urethane-anesthetized rats, high-frequency electrical stimulation of the BLA produced a long-lasting suppression, beginning within 10 min and lasting over 60 min, of tail-pressure-evoked nociceptive unit responses recorded in cingulate and prelimbic mPFC (9 units in 9 rats). This suppression was prevented by NMDA and group II mGluR antagonists and by D2 or D4 antagonists injected into the PFC.
- Source
BMC Neuroscience, 2011
DOI 10.1186/1471-2202-12-115 · PubMed 22085449 · PMC3228703, Fig. 2A-C; Results, 'HFS delivered to the BLA modified pain responses recorded in the PFC'; Fig. 6- Named in the paper
- “basolateral nucleus of the amygdala (BLA)” and “medial prefrontal cortex (mPFC; cingulate and prelimbic areas)”
- Made by
- an AI model reading the paper (claude-opus-5-5, extract@0.3.0), 2026-10-09
- Checked by
a second AI model (claude-opus-5-5) agrees, 2026-10-09
“In rats, BLA high-frequency stimulation produced long-lasting suppression of nociceptive responses in cingulate and prelimbic mPFC (9 units in 9 rats), blocked by the stated antagonists, as Fig. 2, Fig. 6 and the Results report.”
- Status
proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.