clm-y547ycm3c7

LHA (Lateral hypothalamic area) projects to MEA (medial amygdaloid nucleus)

Species: Rat
Result: present
Method: retrograde tracer
Sign: unknown
Evidence: CTb injected into the medial amygdala retrogradely labelled many orexin-immunoreactive neurons in the lateral and perifornical hypothalamus, some of them Fos+ after seizures. This indicates a reciprocal projection back to the medial amygdala.
Source: Selective activation of the hypothalamic orexinergic but not melanin-concentrating hormone neurons following pilocarpine-induced seizures in rats
Frontiers in Neuroscience, 2022
DOI 10.3389/fnins.2022.1056706 · PubMed 36532270 · PMC9751402, Fig. 7C,D
Licence: CC-BY-4.0
Named in the paper: “ORX neurons in LH and perifornical nucleus” and “medial amygdala”
Made by: an AI model reading the paper (claude-opus-5-5, extract@0.3.0), 2026-10-10
Checked by: a second AI model (claude-opus-5-5) agrees, 2026-10-10
“CTb co-injected into the medial amygdala retrogradely labelled seizure-activated orexin neurons (Fig. 7C,D), which the paper interprets as a reciprocal projection.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.