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clm-zezpc33bpd

CL:0000101 functionally connects to CL:0000540

All claims for this connection
Species
Rat
Result
absent
Method
optogenetic circuit mapping
Sign
unknown
Evidence
In spinal slices from naive (uninjured) transgenic rats, optical stimulation of the dorsal root failed to evoke EPSCs in lamina I neurons, although the same cells responded to electrical stimulation of Aδ and C fibers, indicating no functional Aβ input to lamina I under normal conditions.
Source

Optogenetic Activation of Non-Nociceptive Aβ Fibers Induces Neuropathic Pain-Like Sensory and Emotional Behaviors after Nerve Injury in Rats

eneuro, 2018

DOI 10.1523/eneuro.0450-17.2018 · PubMed 29468190 · PMC5819669, Fig. 5B,C

Licence: CC-BY-NC-SA-4.0

Named in the paper
“primary afferent Aβ fibers (ChR2-expressing)” and “Lamina I SDH neurons”
Made by
an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-10
Checked by

a second AI model (claude-opus-5) agrees, 2026-10-10

“In naive slices light evoked no (or negligible) EPSCs in lamina I while electrical stimulation evoked Aδ/C responses.”

Status

proposed

Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.