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BLA (Basolateral amygdalar nucleus) functionally connects to Isocortex
All claims for this connection- Species
- Mouse
- Result
- present
- Method
- optogenetic circuit mapping
- Sign
- unknown
- Evidence
- Halorhodopsin silencing of BLA axon terminals in the vmPFC changed vmPFC calcium activity during observational fear. Shock-suppressed neurons lost their positive freezing correlation, and freezing-positive neurons lost their negative correlation with shock timing. This indicates BLA input shapes the freezing-positive/shock-suppressed subpopulation.
- Source
Ventromedial prefrontal neurons represent self-states shaped by vicarious fear in male mice
Nature Communications, 2023
DOI 10.1038/s41467-023-39081-5 · PubMed 37400435 · PMC10318047, Fig. 6i–p; Results, 'Physiological activity in the vmPFC during inhibition of the ACC-vmPFC and BLA-vmPFC pathways'Licence: CC-BY-4.0
- Named in the paper
- “BLA” and “vmPFC”
- Made by
- an AI model reading the paper (claude-opus-5-5, extract@0.3.0), 2026-10-09
- Checked by
a second AI model (claude-opus-5-5) agrees, 2026-10-09
“Fig. 6i–p shows that BLA terminal silencing removed the positive freezing correlation of shock-suppressed neurons and the negative shock correlation of freezing-positive neurons.”
- Status
proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.