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BLA (Basolateral amygdalar nucleus) functionally connects to PL (Prelimbic area)
All claims for this connection- Species
- Mouse
- Result
- present
- Method
- optogenetic circuit mapping
- Sign
- modulatory
- Evidence
- Optogenetic activation of ChR2-expressing GRP terminals arising from the BLA within the mPFC increased scratching compared with control virus, showing a functional GRPergic BLA-to-mPFC pathway.
- Source
A prefrontal peptidergic circuit for psychogenic itch
Science Advances, 2026
DOI 10.1126/sciadv.aed8901 · PubMed 42585325 · PMC13464479, Fig. 3G- Named in the paper
- “GRP neurons in BLA (BLA→mPFC terminals)” and “mPFC”
- Made by
- an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
- Checked by
a second AI model (claude-opus-5) agrees, 2026-10-09
“Fig. 3G shows opto activation of BLA GRP terminals in mPFC significantly increased scratching versus mCherry controls.”
- Status
proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.