clm-zxz71f78bm

BLA (basal amygdaloid nucleus) functionally connects to ACB (Nucleus accumbens)

Species: Rat
Result: present
Method: optogenetic circuit mapping
Sign: excitatory
Evidence: Brief blue-light pulses applied to ChR2-expressing amygdala fibres in accumbens shell slices evoked postsynaptic currents in accumbens neurons that were abolished by the AMPA-receptor blocker NBQX, and the responses had very short, fixed latencies with no later secondary events, indicating a direct glutamatergic monosynaptic input. The same light-evoked synapses were used throughout for minimal-stimulation, rectification, Naspm and LTD experiments.
Measurements: conduction delay: 0.85 ms (SEM 0.16), n = 156
Source: Maturation of silent synapses in amygdala-accumbens projection contributes to incubation of cocaine craving
Nature Neuroscience, 2013
DOI 10.1038/nn.3533 · PubMed 24077564 · PMC3815713, Fig. 1H–L; Fig. 2E–M; Fig. 3; Fig. 5; Fig. 6
Named in the paper: “BLA” and “NAc shell”
Made by: an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5) agrees, 2026-10-09
“Light-evoked, NBQX-sensitive, short-latency (0.85±0.16 ms, n=156 cells) monosynaptic excitatory responses in NAc shell support this.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.