Rat

BLA (basal amygdaloid nucleus) functionally connects to ACB (Nucleus accumbens)

1 claim from 1 source: 1 found, 0 tested and absent, 0 ambiguous. Evidence: optogenetic circuit mapping.

The claims behind it

clm-zxz71f78bmpresentoptogenetic circuit mappingproposed

Brief blue-light pulses applied to ChR2-expressing amygdala fibres in accumbens shell slices evoked postsynaptic currents in accumbens neurons that were abolished by the AMPA-receptor blocker NBQX, and the responses had very short, fixed latencies with no later secondary events, indicating a direct glutamatergic monosynaptic input. The same light-evoked synapses were used throughout for minimal-stimulation, rectification, Naspm and LTD experiments.

DOI 10.1038/nn.3533 · PubMed 24077564 · PMC3815713, Fig. 1H–L; Fig. 2E–M; Fig. 3; Fig. 5; Fig. 6

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