Mouse

CL:0000617 functionally connects to CL:0000700

1 claim from 1 source: 1 found, 0 tested and absent, 0 ambiguous. Evidence: optogenetic circuit mapping.

The claims behind it

clm-a16xg09a5wpresentoptogenetic circuit mappingproposed

Non-specific photo-stimulation of VTA neurons, which co-activated VGAT-positive GABAergic cells (shown to express ChrimsonR in Fig. 4h), failed to raise accumbal dopamine, whereas blocking GABA-A receptors with intraperitoneal bicuculline before the identical stimulation produced a significant dopamine increase and c-fos activation of ChrimsonR-expressing dopamine neurons, indicating that local VTA GABAergic neurons inhibit VTA dopamine neurons.

DOI 10.3390/ijms23031114 · PubMed 35163036 · PMC8834722, Fig. 3(c,d); Fig. 4h; Fig. 5g–i

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.