Mouse

HIP (Hippocampal region) functionally connects to LA (Lateral amygdalar nucleus)

1 claim from 1 source: 1 found, 0 tested and absent, 0 ambiguous. Evidence: optogenetic circuit mapping.

The claims behind it

clm-srg51y2426presentoptogenetic circuit mappingproposed

Photostimulating ChR2-expressing vHPC terminals evoked AMPAR- and NMDAR-mediated EPSCs in every recorded LA neuron. The responses were abolished by TTX and restored by 4-AP, which indicates monosynaptic input. Feedforward IPSCs were also evoked.

DOI 10.1093/nsr/nwab004 · PubMed 34691732 · PMC8433092, Fig. 3A–H; Supplementary Fig. 7A–C; Fig. 5C–F

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