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LHA (Lateral hypothalamic area) functionally connects to PVH (Paraventricular hypothalamic nucleus)

1 claim from 1 source: 1 found, 0 tested and absent, 0 ambiguous. Evidence: optogenetic circuit mapping.

The claims behind it

clm-4fv4y9ah3bpresentoptogenetic circuit mappingproposed

Photostimulating channelrhodopsin-expressing LHA terminals evoked excitatory postsynaptic currents in PVN oxytocin neurons that were blocked by TTX and rescued by 4-AP, indicating a monosynaptic excitatory input; the same stimulation in vivo also raised the PVN OXT1.7 sensor signal.

DOI 10.1126/sciadv.aeb0400 · PubMed 42341137 · PMC13292991, fig. S4, E to L

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