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sAMY (Striatum-like amygdalar nuclei) functionally connects to PAG (Periaqueductal gray)

1 claim from 1 source: 1 found, 0 tested and absent, 0 ambiguous. Evidence: optogenetic circuit mapping.

The claims behind it

clm-vja4dja43apresentoptogenetic circuit mappingproposed

In brain slices, optogenetic stimulation of ChR2-expressing GABAergic AmgC/M axons in the PAG evoked IPSCs in 16 of 29 CANE-tagged PAG-USV neurons recorded in TTX/4AP (mean ~180 pA at 0 mV); these currents reversed near the chloride equilibrium potential and were eliminated by gabazine, and no EPSCs were seen at -70 mV.

DOI 10.7554/elife.63493 · PubMed 33372655 · PMC7793624, Fig. 5C–F

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.