Mouse

BLA (Basolateral amygdalar nucleus) functionally connects to CP (Caudoputamen)

2 claims from 1 source: 2 found, 0 tested and absent, 0 ambiguous. Evidence: optogenetic circuit mapping.

The claims behind it

clm-86z23yvmqnpresentoptogenetic circuit mappingproposed

Optical stimulation of BLA axons also evoked excitatory postsynaptic currents in putative D2 medium spiny neurons of the dorsomedial striatum (6 cells from 6 mice), but these responses were significantly smaller than in D1 neurons (5 cells from 5 mice) at every light intensity tested.

DOI 10.1038/s41467-023-44322-8 · PubMed 38191518 · PMC10774417, Fig. 2k

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

clm-cgb3fpkrrzpresentoptogenetic circuit mappingproposed

Light activation of ChR2-expressing BLA axons evoked excitatory postsynaptic currents in D1-expressing medium spiny neurons of the dorsomedial striatum, which were larger than those in D2 neurons across stimulation intensities; the AMPA/NMDA ratio of these BLA-evoked currents in D1 neurons increased after chronic circuit activation (9 cells from 3 control mice vs 5 cells from 4 CNO-treated mice).

DOI 10.1038/s41467-023-44322-8 · PubMed 38191518 · PMC10774417, Fig. 2j,k; Fig. 6a-c

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.