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Mouse

MD (Mediodorsal nucleus of thalamus) functionally connects to ACA (Anterior cingulate area)

1 claim from 1 source: 1 found, 0 tested and absent, 0 ambiguous. Evidence: optogenetic circuit mapping.

The claims behind it

clm-hdbh90ahtppresentoptogenetic circuit mappingproposed

Halorhodopsin inhibition of MD axon terminals in the ACC, applied during the demonstrator's foot shocks, removed the shock-related calcium responses in nearly all ACC shock-responding cells imaged in observer mice.

DOI 10.1186/s13041-025-01188-9 · PubMed 40001162 · PMC11853286, Fig. 3a-b

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) disagrees. “The 96.4% figure is the share of shock-responding cells whose response was suppressed during terminal inhibition, not a connection probability, so the number is mislabelled.”