clm-hdbh90ahtp

MD (Mediodorsal nucleus of thalamus) functionally connects to ACA (Anterior cingulate area)

Species: Mouse
Result: present
Method: optogenetic circuit mapping
Sign: unknown
Evidence: Halorhodopsin inhibition of MD axon terminals in the ACC, applied during the demonstrator's foot shocks, removed the shock-related calcium responses in nearly all ACC shock-responding cells imaged in observer mice.
Measurements: connection probability: 0.964, n = 27
Source: Roles of mediodorsal thalamus in observational fear-related neural activity in mouse anterior cingulate cortex
Molecular Brain, 2025
DOI 10.1186/s13041-025-01188-9 · PubMed 40001162 · PMC11853286, Fig. 3a-b
Licence: CC-BY-4.0
Named in the paper: “mediodorsal thalamus (MD)” and “anterior cingulate cortex (ACC)”
Made by: an AI model reading the paper (claude-opus-5-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5-5) disagrees, 2026-10-09
“The 96.4% figure is the share of shock-responding cells whose response was suppressed during terminal inhibition, not a connection probability, so the number is mislabelled.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.