Mouse

PVH (Paraventricular hypothalamic nucleus) functionally connects to CEA (Central amygdalar nucleus)

2 claims from 2 sources: 2 found, 0 tested and absent, 0 ambiguous. Evidence: optogenetic circuit mapping.

The claims behind it

clm-khp52w61qapresentoptogenetic circuit mappingproposed

Optogenetic activation of PVN oxytocin terminals in the central amygdala increased the local OXT1.7 fluorescence, showing oxytocin release onto CeA.

DOI 10.1126/sciadv.aeb0400 · PubMed 42341137 · PMC13292991, fig. S3, H and I

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); not checked yet.

clm-s5s449z2aypresentoptogenetic circuit mappingproposed

Blue-light stimulation of ChR2-expressing PVN oxytocin neuron terminals in the central amygdala raised c-Fos expression in CeA neurons and reduced pain-induced anxiety-like behavior; intra-CeA oxytocin receptor antagonist blocked the behavioral effect of activating PVN oxytocin cells, indicating peptidergic modulatory transmission.

DOI 10.1111/cns.14282 · PubMed 37248645 · PMC10580334, Fig. 6A,G,H; Fig. 5I–N

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); not checked yet.