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Mouse

VM (Ventral medial nucleus of the thalamus) functionally connects to PL (Prelimbic area)

1 claim from 1 source: 1 found, 0 tested and absent, 0 ambiguous. Evidence: optogenetic circuit mapping.

The claims behind it

clm-ggyd11p05mpresentoptogenetic circuit mappingproposed

ChR2 was expressed in VM GRP neurons and light was delivered through a fibre placed over the mPFC; stimulation of these VM axon terminals in the mPFC produced significantly more scratching than in mCherry controls, indicating a functional GRPergic VM-to-mPFC pathway.

DOI 10.1126/sciadv.aed8901 · PubMed 42585325 · PMC13464479, Fig. 3F

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