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ORB (Orbital area) functionally connects to AI (Agranular insular area)

1 claim from 1 source: 1 found, 0 tested and absent, 0 ambiguous. Evidence: optogenetic circuit mapping.

The claims behind it

clm-stb9y2j6gdpresentoptogenetic circuit mappingproposed

Stimulating orbitofrontal axons in insular slices produced excitatory currents in about two thirds of recorded amygdala-projecting insular neurons, with a higher inhibitory-to-excitatory ratio than in accumbens-projecting neurons.

DOI 10.1038/s41467-022-33241-9 · PubMed 36130959 · PMC9492683, Supplementary Fig. 23c–f

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.