Mouse

ORB (Orbital area) functionally connects to BLA glutamatergic principal neurons

1 claim from 1 source: 1 found, 0 tested and absent, 0 ambiguous. Evidence: optogenetic circuit mapping.

The claims behind it

clm-q54ctztbh6presentoptogenetic circuit mappingproposed

Blue-light activation of ChR2-expressing orbitofrontal axons in slices evoked excitatory postsynaptic currents in BLA pyramidal neurons; the responses disappeared with tetrodotoxin and returned with 4-aminopyridine, indicating a monosynaptic glutamatergic (AMPAR/NMDAR-mediated) input.

DOI 10.1038/s41398-020-0837-3 · PubMed 32424318 · PMC7235080, Fig. 1c,d; Fig. 2f-k

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.