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VTA (Ventral tegmental area) functionally connects to CEA (Central amygdalar nucleus)

1 claim from 1 source: 1 found, 0 tested and absent, 0 ambiguous. Evidence: optogenetic circuit mapping.

The claims behind it

clm-fs7wm83gvmpresentoptogenetic circuit mappingproposed

Blue-light stimulation of ChR2-expressing VTA glutamatergic axon terminals in the CeA raised c-Fos expression in CeA neurons relative to unstimulated controls, and the same terminal stimulation drove rapid, frequency-dependent NREM-to-wake transitions and sustained wakefulness, indicating a functional driving input from VTA glutamatergic neurons to the CeA.

DOI 10.3389/fnins.2022.850193 · PubMed 35527820 · PMC9070111, Fig. 4C,D; Fig. 5B-F

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.