Mouse

PA (Posterior amygdalar nucleus) functionally connects to VMH (Ventromedial hypothalamic nucleus)

1 claim from 1 source: 1 found, 0 tested and absent, 0 ambiguous. Evidence: optogenetic circuit mapping. Strongest reported: strong.

The claims behind it

clm-e25t4mv2cppresentoptogenetic circuit mappingstrength: strongproposed

Photostimulation of Chronos-expressing AHiPM terminals in acute slices reliably evoked postsynaptic currents in tdTomato-identified Esr1 neurons of VMHvl when held at the reversal potential for inhibition (-70 mV), with no response detectable at the reversal potential for excitation (0 mV), indicating a purely excitatory and at least partly monosynaptic input; AMPA/NMDA ratios, synaptic integration, and ex vivo and in vivo (fEPSP) LTP/LTD were measured at this input.

DOI 10.1073/pnas.2011782117 · PubMed 32973099 · PMC7568289, Fig. 2 I–M; SI Appendix Fig. S2; Fig. 4 B–G, L, M, O

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