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Mouse

PB (Parabrachial nucleus) functionally connects to CEAc (Central amygdalar nucleus, capsular part)

1 claim from 1 source: 1 found, 0 tested and absent, 0 ambiguous. Evidence: optogenetic circuit mapping.

The claims behind it

clm-69ftc4zcdepresentoptogenetic circuit mappingproposed

In slices, light activation of ChR2-expressing PBelo CGRP axons in the CeAlc evoked excitatory postsynaptic currents and raised firing in CeAlc neurons; both responses were abolished by CNQX and APV, indicating glutamatergic transmission. In vivo photostimulation of either the PBelo cell bodies or their CeAlc terminals increased Fos in the CeAlc.

DOI 10.1038/nature12596 · PubMed 24121436 · PMC3878302, Fig. 4b; Supplementary Fig. 14

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.