Mouse

PB (Parabrachial nucleus) functionally connects to VPMpc (Ventral posteromedial nucleus of the thalamus, parvicellular part)

1 claim from 1 source: 1 found, 0 tested and absent, 0 ambiguous. Evidence: optogenetic circuit mapping.

The claims behind it

clm-6fmpd2t7r2presentoptogenetic circuit mappingproposed

Optogenetic stimulation of CGRP parabrachial terminals in slices from CalcaFLPo::Oprm1Cre mice evoked EPSCs in almost all recorded Oprm1 VPMpc neurons (41 of 43). The responses were blocked by AMPA and NMDA receptor antagonists and were restored by 4AP after TTX.

DOI 10.1038/s41467-025-63464-5 · PubMed 41006304 · PMC12475432, Fig. 1i–m; Supplementary Fig. 3

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.