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AI (Agranular insular area) functionally connects to CEAm (Central amygdalar nucleus, medial part)

1 claim from 1 source: 1 found, 0 tested and absent, 0 ambiguous. Evidence: optogenetic circuit mapping.

The claims behind it

clm-da9418gd3gpresentoptogenetic circuit mappingproposed

Optogenetic activation of insular axons evoked EPSCs in CeM neurons that persisted under TTX+4AP and were blocked by AP5+NBQX, showing direct glutamatergic input. IPSCs disappeared under TTX+4AP, so they were polysynaptic.

DOI 10.1038/s41467-023-40517-1 · PubMed 37604802 · PMC10442438, Fig. 4a-g

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.