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PL (Prelimbic area) functionally connects to PAG (Periaqueductal gray)

1 claim from 1 source: 1 found, 0 tested and absent, 0 ambiguous. Evidence: optogenetic circuit mapping.

The claims behind it

clm-w9bkx881wppresentoptogenetic circuit mappingproposed

A single blue light pulse applied to ChR2-expressing PrL terminals in the lateral/ventrolateral PAG evoked an EPSC in PAG neurons; the response was blocked by TTX and recovered with 4-AP, consistent with a monosynaptic excitatory projection.

DOI 10.1172/jci166356 · PubMed 36917193 · PMC10145931, Supplemental Fig. 6B–D

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