Rat

DR (Dorsal nucleus raphe) projects to PL (Prelimbic area)

1 claim from 1 source: 1 found, 0 tested and absent, 0 ambiguous. Evidence: retrograde tracer.

The claims behind it

clm-t09r7mgjxspresentretrograde tracerproposed

Bilateral injection of retrograde AAV-CAG-tdTomato into medial prefrontal cortex labelled neurons in the dorsal raphe, clustered mainly in the interfascicular/ventromedial DRN, showing that DRN neurons project to mPFC. Most of these retrogradely labelled cells were Tph2-positive (serotonergic) and more than 73% were nNOS-positive.

DOI 10.1038/s41598-025-99181-8 · PubMed 40275074 · PMC12022358, Fig. 1A–D; Fig. 3A–C

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.